The effect of milk and skim milk intake on serum lipids and apoproteins in young females.

The effect of milk and skim milk intake on serum lipid and apoprotein levels was investigated in young females with consideration of each subject's menstrual period. When milk and dairy products were not allowed, the serum cholesterol concentration tended to decrease in high density lipoprotein (HDL) and very low density lipoprotein (VLDL), the triglyceride concentration tended to increase in HDL and low density lipoprotein (LDL), the phospholipid concentration showed no change, and the apoB, apoC-III and apoE significantly decreased. In the milk group, VLDL cholesterol and phospholipid concentrations were increased with a significant increase in the apoB concentration after intake of 200 ml/day of milk for one menstrual period, and these levels did not change when the milk intake was doubled. VLDL phospholipid increased and apoE decreased after the intake of 20 g/day of skim milk, and LDL cholesterol and HDL phospholipid concentrations tended to decrease when the skim milk intake was doubled.